The Computational Chemistry and Biology (CCB) Core Facility provides a wide array of advanced tools and services for computational-based simulations and modeling of chemical and biological systems. Located on the Anschutz Medical Campus of the University of Colorado in the new Skaggs School of Pharmacy and Pharmaceutical Sciences building, the CCB Core offers specialized expertise to researchers in both academia and the biotech/pharmaceutical industry to:
A major goal of the CCB Core is to aid in the discovery and design of novel small molecule drugs by rapidly identifying and refining promising compounds utilizing a variety of strategies.
The CCB Core specializes in the production of clear, concise, publication-quality graphics for grant submissions, manuscripts, reviews, and presentations.
The CCB Core can perform early assessment of novel drug candidates by calculating predicted absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties for collections of molecules
The CCB Core utilizes validated scientific tools to aid in every step of macromolecule research.
Determining the structure and properties of a macromolecule, such as enzymes, antibodies, DNA, or RNA, is fundamental to understanding structure-activity relationships, protein-protein interactions, DNA/RNA binding, and small molecule design.