Melanie Joy PharmD, PhD

Professor Pharmaceutical Science Innovation and Commercialization Director

Stacey Tuey, B.S.: PhD Student in Pharmaceutical Sciences
Stacey completed her BS degree in Chemistry from California State Polytechnic University of Pomona. Her research focuses on investigating the effects of vitamin D on drug disposition pathways in the chronic kidney disease population. This translational research includes in vitro approaches to understand underlying mechanism of drug metabolism and transport and applies this to a clinical study. Other emphasis areas include pharmacokinetic and physiologically based pharmacokinetic (PBPK) modelling to understand how these mechanisms affect drug concentrations and responses in humans.
Lauren E. Thompson, BS: PhD Student in Pharmaceutical Sciences
Lauren completed her BS degree in Biochemistry with a minor in Mathematics from Denison University in Ohio. Lauren’s research focuses on cisplatin induced acute kidney injury in cancer patients. She has started work investigating nephroprotectant compounds in a mouse cancer model of cisplatin-induced acute kidney injury. She is additionally leading a clinical trial with the goals of elucidating pharmacokinetic and pharmacogenetic determinants that govern renal exposure to cisplatin, as well as the impact of 5-hydroxytryptamine antagonists, a class of anti-emetic drugs. A better understanding of the key processes and pathways involved in renal cisplatin exposure will lead to therapy adjustments to decrease renal exposure and toxicity, while maintaining efficacy.