Pharmaceutical Sciences Faculty

Research Focus: Behavioral responses to alcohol Quantitative RNA sequencing Systems genetics

Research Focus: Chemical synthesis of heterocyclic compounds Computational-based design of novel small molecules Disrupting drug resistance mechanisms in cancer (DNA damage response) Targeting adaptive proteins and pathways in hypoxia (metabolic reprogramming)

Research Focus: Metabolomics lipidomics and proteomics Novel informatics strategies applied to metabolomics Nutrimetabolomics Role of oxylipins in inflammatory immune and lung disease Understanding role of host:microbiome metabolism in health and disease

Research Focus: Environmental causes of neurodegeneration e.g. maneb exposure Metabolic consequences of mitochondrial dysfunction Proteostasis and neurodegeneration Thiol redox dysregulation in mechanisms of toxicity

Research Focus: Genetics of substance use disorders Multi-omics data integration Statistical methods and bioinformatics techniques for studying complex genetic traits Transcriptomics and systems genetics

Research Focus: Immunology and nanoformulations/drug delivery systems Molecular biology immunology and nanotechnology

Research Focus: Cells as carriers of drugs and diagnostics Immune recognition of nanoparticles Isolation of biomarkers and cells from bulk fluids

Research Focus: Creating extensive DNA and RNA sequence information for rat strains to be used in systems analysis of physiology and behavior Development of medications to be used for prevention of relapse in alcoholics Development of medications to treat chronic pain syndromes and reduce opiate use The genetic predisposing factors for alcoholism and other addictions