Pharmaceutical Sciences Faculty

Research Focus: Biomarkers Discovery and Translation of Novel Treatment Approaches to Kidney Diseases Drug-induced kidney toxicities Genetics of drug efficacy and toxicity In Vivo and In Vitro Drug Metabolism and Transport in Kidney Innovation and entrepreneurship Pharmacokinetics and Pharmacodynamics Preclinical and clinical development of drugs and biologics

Research Focus: Nanomedicines for drug delivery gene delivery and imaging Novel drug delivery systems: Nanoparticles microparticles and implants. Novel therapies for diabetic retinopathy macular degeneration and cancers. Ocular respiratory and brain drug discovery delivery and development

Research Focus: Cancer Pharmacology of Natural Products Public Science Communication Science and Medical Journalism

Research Focus: Drug Design Drug Mechanism(s) of Action HTS/HCS Drug Discovery In vitro and In vivo Pharmacokinetics and Toxicology In vitro and In vivo Pharmacology Molecular and Cancer Biology Organic and Medicinal Chemistry

Research Focus: cytochrome P450 enzymes drug metabolism and disposition enzymology Pharmacokinetics

Research Focus: Biophysical characterization of protein vaccine stability and aggregation Structure stability and aggregation of protein drug substances and drug products Structure-function-disease analysis of dystrophin and muscular dystrophy

Research Focus: Complement-mediated tissue damage Extracellular vesicles and organ-organ crosstalk Immunotherapy and natural immunosuppression Innate immunity and chronic liver diseases

Research Focus: Environmental causes of neuronal injury Mitochondrial (dys)function and oxidative stress in epilepsy and neurodegeneration Neuroinflammation and redox signaling Redox-based small molecule therapeutics

Research Focus: Ecological Roles of Natural Products Host-Microbiome-Environment Interactions Mass Spectrometry Tools for Microbial Systems

Research Focus: Behavioral responses to alcohol Quantitative RNA sequencing Systems genetics

Research Focus: Chemical synthesis of heterocyclic compounds Computational-based design of novel small molecules Disrupting drug resistance mechanisms in cancer (DNA damage response) Targeting adaptive proteins and pathways in hypoxia (metabolic reprogramming)

Research Focus: Metabolomics lipidomics and proteomics Novel informatics strategies applied to metabolomics Nutrimetabolomics Role of oxylipins in inflammatory immune and lung disease Understanding role of host:microbiome metabolism in health and disease

Research Focus: Environmental causes of neurodegeneration e.g. maneb exposure Metabolic consequences of mitochondrial dysfunction Proteostasis and neurodegeneration Thiol redox dysregulation in mechanisms of toxicity

Research Focus: Genetics of substance use disorders Multi-omics data integration Statistical methods and bioinformatics techniques for studying complex genetic traits Transcriptomics and systems genetics

Research Focus: Cells as carriers of drugs and diagnostics Immune recognition of nanoparticles Isolation of biomarkers and cells from bulk fluids