Department Faculty

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Rajesh Agarwal PhD

Professor Cancer Prevention and Control Program Co-Leader
Research Focus: Cancer Biology Cancer Pharmacology Warfare vesicants

Peter Anderson PharmD

Professor
Research Focus: Antiviral drug pharmacokinetic-pharmacodynamic relationships in humans New assays for drug/metabolite quantification in unique compartments in humans Using drug concentrations to assess adherence to antiviral therapies

Christina Aquilante PharmD

Professor Director of Pharmacogenomics for the Colorado Center for Personalized Medicine
Research Focus: Cardiovascular Diseases Clinical Pharmacogenomics Heart Transplantation

David Bain PhD

Professor Vice-Chair
Research Focus: Biophysical characterization of therapeutic macromolecules Mechanisms of transcriptional regulation Thermodynamics of protein-protein and protein-DNA interactions

Kristina Brooks PharmD

Assistant Professor
Research Focus: biomarkers drug-drug interactions HIV pediatrics Pharmacokinetics pregnant women tuberculosis

Jared Brown PhD

Professor Toxicology Graduate Program Director, T32 Training Program in Molecular and Systems Toxicology Director, Colorado Center for Nanomedicine and Nanosafety Co-Director
Research Focus: Bladder Cancer Chronic kidney disease of unknown origin (CKDu) Inflammation and immune responses to particulates Mast cells and allergy Nanomedicine and Nanosafety

Shaodong Dai PhD

Professor
Research Focus: CAR T and engineered T cell therapies of autoimmune diseases Mechanisms of T cell mediated metal hypersensitivities Mechanisms of T cell recognition of autoantigens in Type 1 diabetes and RA Redox signaling and drug design in the immune diseases and infectious diseases

Thomas Delong Dr. rer. nat

Assistant Professor
Research Focus: Autoantigen discovery in autoimmune diseases Mass spectrometry Pathogenesis of Type 1 Diabetes Post-translational modifications T cell immunology

Kristofer Fritz PhD

Associate Professor
Research Focus: Mechanisms of alcoholic liver disease Metabolic dysregulation of liver and kidney function Regulatory nature of sirtuin activity and protein acetylation Utilizing mass spectrometry to investigate proteomics & post-translational modifications

Melanie Joy PharmD, PhD

Professor Pharmaceutical Science Innovation and Commercialization Director
Research Focus: Discovery and Translation of Novel Treatment Approaches to Kidney Diseases In Vivo and In Vitro Drug Metabolism and Transport in Kidney Nephrotoxicity / Biomarkers Pharmacokinetics/Pharmacodynamics/Pharmacogenomics

Uday Kompella PhD, FARVO, FAAPS

Colorado Center for Nanomedicine and Nanosafety Co-Director and Co-founder Professor of Pharmaceutical Sciences, Ophthalmology, and Bioengineering
Research Focus: Nanomedicines for drug delivery gene delivery and imaging Novel drug delivery systems: Nanoparticles microparticles and implants. Novel therapies for diabetic retinopathy macular degeneration and cancers. Ocular respiratory and brain drug discovery delivery and development

David Kroll PhD

Professor Master’s Degree and Certificate Programs in Pharmacy & Pharmaceutical Sciences Director
Research Focus: Cancer Pharmacology of Natural Products Public Science Communication Science and Medical Journalism

Daniel LaBarbera PhD

Professor Director CU AMC Center for Drug Discovery, Co-Director, Drug Discovery and Development Shared Resource (D3SR)
Research Focus: Drug Design Drug Mechanism(s) of Action HTS/HCS Drug Discovery In vitro and In vivo Pharmacokinetics and Toxicology In vitro and In vivo Pharmacology Molecular and Cancer Biology Organic and Medicinal Chemistry

Jed Lampe PhD

Associate Professor
Research Focus: cytochrome P450 enzymes drug metabolism and disposition enzymology Pharmacokinetics

Krishna Mallela PhD

Professor, Pharmaceutical Sciences Graduate Program Associate Director
Research Focus: 2D NMR spectroscopy of antibody therapeutics Biophysical characterization of protein vaccine stability and aggregation Structure stability and aggregation of protein drug substances and drug products Structure-function-disease analysis of dystrophin and muscular dystrophy

Rebecca McCullough PhD

Assistant Professor Toxicology Graduate Program Associate Director
Research Focus: Complement-mediated tissue damage Extracellular vesicles and organ-organ crosstalk Immunotherapy and natural immunosuppression Innate immunity and chronic liver diseases

Manisha Patel PhD

Associate Dean for Research and Graduate Studies, Professor
Research Focus: Environmental causes of neuronal injury Mitochondrial (dys)function and oxidative stress in epilepsy and neurodegeneration Neuroinflammation and redox signaling Redox-based small molecule therapeutics

Vanessa Phelan PhD

Assistant Professor
Research Focus: Ecological Roles of Natural Products Host-Microbiome-Environment Interactions Mass Spectrometry Tools for Microbial Systems

Richard Radcliffe PhD

Professor
Research Focus: Behavioral responses to alcohol Quantitative RNA sequencing Systems genetics

Philip Reigan PhD

Associate Professor Computational Chemistry and Biology Core Facility Director
Research Focus: Chemical synthesis of heterocyclic compounds Computational-based design of novel small molecules Disrupting drug resistance mechanisms in cancer (DNA damage response) Targeting adaptive proteins and pathways in hypoxia (metabolic reprogramming)

Nichole Reisdorph PhD

Professor Mass Spectrometry Facility Director
Research Focus: Metabolomics lipidomics and proteomics Novel informatics strategies applied to metabolomics Nutrimetabolomics Role of oxylipins in inflammatory immune and lung disease Understanding role of host:microbiome metabolism in health and disease

James Roede PhD

Associate Professor
Research Focus: Environmental causes of neurodegeneration e.g. maneb exposure Metabolic consequences of mitochondrial dysfunction Proteostasis and neurodegeneration Thiol redox dysregulation in mechanisms of toxicity

Laura Saba PhD

Associate Professor Director, Graduate Program in Pharmaceutical Sciences
Research Focus: Genetics of substance use disorders Multi-omics data integration Statistical methods and bioinformatics techniques for studying complex genetic traits Transcriptomics and systems genetics

Robert Scheinman PhD

Associate Professor
Research Focus: Immunology and nanoformulations/drug delivery systems Molecular biology immunology and nanotechnology

Dmitri Simberg PhD

Professor Colorado Center for Nanomedicine and Nanosafety Co-Director
Research Focus: Cells as carriers of drugs and diagnostics Immune recognition of nanoparticles Isolation of biomarkers and cells from bulk fluids
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