There is a growing sentiment in the field that in order to increase the availability of nanodrugs for patients, the biological, pathophysiological, immunological and manufacturing/regulatory barriers to effective translation need to be addressed.
The goals of the two-day Mechanisms and Barriers in Nanomedicine workshop are to:
Talk | Speaker |
Fundamental issues in nanomedicine | Anchordoquy |
Complement and immune uptake of nanomedicines: lessons from iron oxide nanoworms | Dmitri Simberg |
Keynote: Tumor-penetrating peptides in nanoparticle targeting | Erkki Ruoslahti |
Where the wild things are: Perivascular regulation of tumor cell dormancy and drug resistance | Cyrus Ghajar |
Immunotherapy targeting tumor microenvironment and opportunities for nanomedicine | Stephen Dow |
Improving nano-drugs' therapeutic efficacy through their interaction with tumor microenvironment | Chezy Barenholz |
Physical and chemical mechanisms of targeting selectivity for mRNA nanomedicines for tumor immunotherapy | Heinrich Haas |
Nanobioconjugates delivered through multiple biobarriers regulate laminin-411 - Notch pathways | Julia Ljubimova |
Exploiting cells in the tumor microenvironment for nanovector based therapy | Biana Godin |
The 4S parameters in the rational design of nanomedicines | Paolo Decuzzi |
Biologics and peptides by a novel encapsulation process | Robert Prud'homme |
Optimizing nanoparticle delivery of chemotherapeutics - The clinical challenge | Alberto Gabizon |
Impact of nanoparticles on the tumor immunologic milieu: Promise and peril | Irene La-Beck |
Nanoparticle-based MRI on tumor associated macrophages: preclinical and clinical utility | Natalie Serkova |
Translation of a cancer nanotherapeutic into the clinic: A view from the trenches | Len Pagliaro |
Preclinical immunotoxicity studies of nanotechnology-formulated drugs | Marina Dobrovolskaia |
Perspective on nanomedicine climate and the science advances | Dorothy Farrell |
Hyperthermia approaches for enhanced delivery of polymer therapeutics | Hamid Ghandehari |
Biophysical barriers in respiratory drug delivery | Hugh Smyth |
To target or not to target: Lessons from RNAi-based targeted lipid-based nanoparticles | Dan Peer |
Extracellular vesicles-mediated penetration of therapeutic compounds in solid tumors | Ji Ho (Joe) Park |
Nanoparticle-prodrug combination approach for treating neuroblastoma | Michael Chorny |
Nanoghosts as a natural nonviral gene delivery platform for targeting cancers | Marcelle Machlouf |
Best poster talks | |
Impact of Motif Organization on the Formation and Stability of Silk-Elastin like Protein Polymer Nanogels | Martin Jensen (University of Utah) |
Nanoscale Colloids & Particles for High Intensity Focused Ultrasound (HIFU)-Initiated Imaging | Nicholas Blum (University of Colorado Boulder) |
Hearing and seeing nanoparticle targeting with photoacoustic imaging | Jack Ho (Princeton University) |
Dmitri Simberg
University of Colorado
Thomas Anchordoquy
University of Colorado
Jared Brown
University of Colorado
Moien Moghimi
University of Copenhagen
Shadi Farhangrazi
Biotrends International
University of Denver