PhD, Pharmacology and Toxicology, Purdue University
Post-doc, Neuroscience, Duke University.
Affiliations
University of Colorado, Program in Neuroscience
National Jewish Medical & Research Center, Department of Medicine
Research Interest
Environmental causes of neuronal injury
Mitochondrial (dys)function and oxidative stress in epilepsy and neurodegeneration
Neuroinflammation and redox signaling
Redox-based small molecule therapeutics
Publications and Presentations
Castello PR, Drechsel D, Patel M. Mitochondria are a major source of paraquat-induced reactive oxygen species production. J. Biol. Chem. Vol 282 (19): 14186-14193, 2007.
Ryan KR, Backos DS, Reigan P, Patel M. Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis. J. Neurosci. 32(33):11250-8; 2012.
Pearson JN, Rowley S, Liang L-P, White AM, Day BJ, Patel M. Oxidative stress-mediated mitochondrial dysfunction and neuronal loss contribute to cognitive deficits in experimental temporal lobe epilepsy Neurobiol. Dis. 82:289-297; 2015.
Skaggs School of Pharmacy and Pharmaceutical Sciences