The Colorado Center for Nanomedicine and Nanosafety will promote collaborative effort, stimulate learning, and advance multidisciplinary research and education in the areas of basic and applied nanomedicine and nanosafety, between academic labs and the local and national biotech and pharma companies.
Sponsors: Skaggs School of Pharmacy and Pharmaceutical Sciences, ALSAM foundation
Synthesis and evaluation of magnetic nanoparticles, MRI contrast agents, near infrared probes, ultrasound microbubbles, liposomes, PLGA nanoparticles
Toxicity and safety assessment of nanomaterials including cell viability, cellular uptake/dosimetry, cellular and tissue imaging, hyperspectral imaging, biodistribution, inflammatory responses.
Small molecule, peptide, protein, and nucleic acid loaded nanoparticles for enhanced drug/gene delivery; ligand functionalized nanoparticles for targeted delivery; pure drug nanoparticles and nanotubes; polymeric, protein, and viral capsid nanoparticles.
Equipment available to members of the CCNN:
List to be expanded.
March 24th, 2017
April 26th, 2018
April 26th, 2019
April 30th, 2020 - cancelled due to COVID-19.
Research in the Brown lab is focused on immune responses to particles including nanoparticles, air pollution, silica and coal dust. In particular, our research group investigates the role of innate immune cells, including mast cells and macrophages, in response to particles. In addition, we are interested in understanding the toxicity of engineered nanomaterials as well as their use in drug delivery and treatment of cancer.