Shaodong Dai

Shaodong Dai

Associate Professor
Pharmaceutical Sciences
  • Skaggs School of Pharmacy and Pharmaceutical Sciences

Email Address:

Primary Phone: 303-724-3276

Recent Publications

Office Location:

Pharmacy and Pharmaceutical Sciences Building (V20)
Second Floor Room 2121

Research Interests:

  • Mechanisms of T cell mediated metal hypersensitivities
  • Mechanisms of T cell recognition of autoantigens in Type 1 diabetes and RA
  • CAR T and engineered T cell therapies of autoimmune diseases
  • Redox signaling and drug design in the immune diseases and infectious diseases

Representative publications:

Salinas G, Gao W, Wang Y, Bonilla M, Yu L, Novikov A, Virginio VG, Ferreira HB, Vieites M, Gladyshev VN, Gambino D, Dai S. (2017) The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I). Antioxid Redox Signal. 27(18):1491-1504. (Cover Story)

Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. (2018) C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 115(1):162-167.

Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau DB, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. (2019) How C-terminal additions to insulin B-chain fragments create super-agonists for T cells in mouse and human type-1 diabetes. Science Immunology, 2019 Apr 5;4(34). (Cover Story)