Krishna Mallela

Krishna Mallela PhD

Associate Professor
Pharmaceutical Sciences
  • Skaggs School of Pharmacy and Pharmaceutical Sciences

Recent Publications


Office Location:

Pharmacy and Pharmaceutical Sciences Building (V20)
Fourth Floor Room 4123

Research Interests:

  • Structure-function-disease analysis of dystrophin and muscular dystrophy
  • Structure, stability, and aggregation of protein drug substances and drug products
  • 2D NMR spectroscopy of antibody therapeutics
  • Biophysical characterization of protein vaccine stability and aggregation

Representative publications:

SM Singh, S Bandi, and KMG Mallela, The N-terminal flanking region modulates the actin binding affinity of the utrophin tandem calponin-homology domain, Biochemistry, 56 (2017) 2627-2636.

SM Singh, S Bandi, and KMG Mallela, The N- and C-terminal domains differentially contribute to the structure and function of dystrophin and utrophin tandem calponin-homology domains, Biochemistry, 54 (2015) 6942-6950.

S Bandi, SM Singh, and KMG Mallela, Interdomain linker determines primarily the structural stability of dystrophin and utrophin tandem calponin-homology domains rather than their actin-binding affinity, Biochemistry, 54 (2015) 5480-5488.