David Ross

David Ross PhD

Professor and Chair
Pharmaceutical Sciences
  • Skaggs School of Pharmacy and Pharmaceutical Sciences

Email Address: david.ross@cuanschutz.edu

Primary Phone: 303-724-7265

Recent Publications

Office Location:

Pharmacy and Pharmaceutical Sciences Building (V20)
Second Floor Room 2132A

Research Interests:

  • Quinones, quinone reductases, selective toxicity of antitumor agents, drug development, targeting of antitumor agents, pharmacogenomics. My laboratory is focused on understanding the role of the quinone reductases in physiological systems and the mechanisms underlying the toxicity of quinones. We then apply that knowledge to a number of different projects in antitumor drug development, environmental toxicology, neurodegeneration and cellular signaling.

Representative publications:

Redox modulation of NQO1. David Siegel , Donna D. Dehn, Samantha S. Bokatzian, Kevin Quinn, Donald S. Backos, Andrea Di Francesco, Michel Bernier, Nichole Reisdorph, Rafael de Cabo, David Ross. PLoS One, 2018 https://doi.org/10.1371/journal.pone.0190717,

Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch. Frontiers in Physiology 8, 595,2017 https://doi.org/10.3389/fphys.2017.00595