David Bain

David Bain PhD

Professor, Vice-Chair
Pharmaceutical Sciences
  • Skaggs School of Pharmacy and Pharmaceutical Sciences

Email Address: david.bain@cuanschutz.edu

Primary Phone: 303-724-6118

Recent Publications

Office Location:

Pharmacy and Pharmaceutical Sciences Building (V20)
Fourth Floor Room 4117

Research Interests:

  • Mechanisms of transcriptional regulation
  • Thermodynamics of protein-protein and protein-DNA interactions
  • Biophysical characterization of therapeutic macromolecules

Representative publications:

Hopkins MM, Lambert CL, Bee JS, Parupudi A, Bain DL (2018) Determination of interaction parameters for reversibly self-associating antibodies: A comparative analysis. J Pharm Sci, 107, 1820-1830.

De Angelis, RW, Maluf, NK, Yang, Q, Lambert, JR, and Bain, DL (2015) Glucocorticoid receptor dissociation kinetics measured in vitro reveal exchange on the second time scale. Biochemistry, 54, 5306-5314.

Bain DL, Yang Q, Connaghan KD, Robblee JP, Miura MT, Degala GD, Lambert JR, Maluf NK. (2012) Glucocorticoid receptor-DNA interactions: Binding energetics are the primary determinant of sequence-specific transcriptional activity. J Mol Biol, 422, 18-32