Julio Aguado PhD

Publications and Presentations

1. Aguado, J., Amarilla, A., Taherian-Fard, A., Albornoz, E., Tyshkovskiy, A., Schwabenland, M., Chaggar, H., Modhiran, N., Gómez-Inclán, C., Javed, I., Baradar, A., Liang, B., Dharmaratne, M., Pietrogrande, G., Padmanabhan, P., Freney, M., Parry, R., Sng, J., Isaacs, A., Khromykh, A, Rojas-Fernandez, A., Davis, T., Prinz, M., Bengsch, B., Gladyshev, V., Woodruff, T., Mar, J., Watterson, D. & Wolvetang, E. Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging 3, pages 1561–1575 DOI: 10.1038/s43587-023-00519-6 (2023).

2. Aguado, J., Sola-Carvajal, A., Cancila, V., Revêchon, G., Fern Ong, P., Jones-Weinert, C.W., Wallén Arzt, E., Lattanzi, G., Dreesen, O., Tripodo, C., Rossiello, F., Eriksson, M., & d’Adda di Fagagna, F. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome. Nature Communications, 10, 4990 (2019).

3. Aguado, J., Chaggar, H., Gómez-Inclán, C., Shaker, M., Leeson, H., Mackay-Sim, A. & #Wolvetang, E. Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids. Aging Cell, DOI: 10.1111/acel.13468 (2021).

4. Aguado, J., d’Adda di Fagagna, F. & Wolvetang, E. Telomere transcription in Ageing. Ageing Research Reviews, Vol. 62, 101115 (2020).

5. Aguado, J., Gómez-Inclán, C., Leeson, H., Lavin, M., Shiloh, Y. & #Wolvetang, E. The hallmarks of aging in Ataxia- Telangiectasia. Ageing Research Reviews, 79 101653, (2022).

6. *Nguyen, Q., *Aguado, J., Iannelli, F., Suzuki A, Rossiello, F., d’Adda di Fagagna, F. & Carninci, P. Target-Enrichment Sequencing for Detailed Characterization of Small RNAs. Nature Protocols, 13, pages 768–786 (2018).

7. Aguado, J., & Wolvetang, E. Exploring aging interventions in human brain organoids. Aging, 14 (4), 1592-1593 (2022).