• Pharmacokinetics: the study of the time course of absorption, distribution, metabolism, and excretion (i.e., disposition) of drugs in the body.
  • Pharmacodynamics: the study of the relationship between drug concentrations and drug response in the body.
  • Pharmacogenomics: the study of how genetic variation influences interindividual variability in drug disposition and response.

Academic and private investigators who wish to incorporate pharmacokinetics and pharmacogenomics into their research programs are invited to contact the Center for opportunities to collaborate with members.

Headshot of Lauren Vanderlinden

Lauren Vanderlinden MS

Research Instructor
  • Skaggs School of Pharmacy and Pharmaceutical Sciences
  • Center for Innovative Design & Analysis

Email Address:lauren.vanderlinden@cuanschutz.edu

Primary Phone:303-724-3626

Mailing Address:
  • CU Anschutz

Pharmacy and Pharmaceutical Sciences Building

12850 East Montview Boulevard

Aurora, CO 80045

Lauren is a research instructor in the Center for Innovative Design & Analysis at the Colorado School of Public Health. She has over 11 years of experience as a biostatistician conducting research on statistical methods related to the development of precision medicine. She constructs experimental designs, manages data in a proficient manner, executes a variety of statistical analyses, and interprets the results in a biologically meaningful way for the advancement of scientific discovery. She focuses on applying statistical approaches to integrate a variety of high-throughput ‘omic and physiological data. She has extensive experience in constructing, validating, and comparing biological transcriptional networks and has worked in a variety of research models ranging from recombinant inbred animal models to large longitudinal human cohort studies. Statistically determining both the genetic and environmental underpinning of disease is the ultimate goal of her research.

Areas of Expertise

  • Omics data analysis

Education, Licensure & Certifications

  • MS, Biostatistics, University of Colorado Anschutz Medical Campus
  • BA, Chemistry, University of Colorado Boulder
  • BA, Mathematics, University of Colorado Boulder

Pharmacokinetics

  • HPLC with UV, Fluorescence, PDA
  • LC-MS (ThermoScientific MSQ)
  • LC-MS-MS (ThermoScientific TSQ Quantum)
  • UPLC-MS-MS (ThermoScientific Accela-TSQ Vantage)

Pharmacogenomics

  • DNA isolation
  • Polymerase Chain Reaction
  • Pyrosequencing

Pharmacokinetics

  • NONMEM
  • PDx-POP
  • Pirana
  • PsN
  • Xpose4
  • Phoenix Academic Bundle
  • Phoenix WinNonlin
  • NLME
  • IVIVC
  • Connect
  • Simcyp Simulator
  • Simcyp Animal
  • Boomer

Pharmacogenomics

  • Biotage Primer Design Software
  • PHASE (for haplotype analysis)

Study Design and Statistical Analysis

  • PASS Power and Sample Size Software
  • SPSS Statistical Analysis Software
  • SAS Statistical Analysis Software