Center for Translational Pharmacokinetics and Pharmacogenomics
The center is a collaborative group of pharmacokinetics and pharmacogenomics experts with the scientific and technical expertise, knowledge, and physical resources to conduct high-level translational research in these fields.
- Pharmacokinetics: the study of the time course of absorption, distribution, metabolism, and excretion (i.e., disposition) of drugs in the body.
- Pharmacodynamics: the study of the relationship between drug concentrations and drug response in the body.
- Pharmacogenomics: the study of how genetic variation influences interindividual variability in drug disposition and response.
Academic and external investigators working in preclinical and clinical development of drugs and biologics, or conducting independent research, can contact Center members directly for opportunities to collaborate and develop appropriate strategies for integration of pharmacokinetics, pharmacodynamics and pharmacogenetics.
Uday Kompella PhD, FARVO, FAAPS
Colorado Center for Nanomedicine and Nanosafety Co-Director and Co-founder
Professor of Pharmaceutical Sciences, Ophthalmology, and Bioengineering
- Department of Pharmaceutical Sciences
Email Address:uday.kompella@cuanschutz.edu
Primary Phone:303-724-4028
Nanomedicine and Drug Delivery Laboratory
Mailing Address:
- CU Anschutz
Pharmacy and Pharmaceutical Sciences Building
12850 East Montview Boulevard
Lab: V20-4460D(N)/4470
Office: V20-4129
Aurora, CO 80045
Education, Licensure & Certifications
- PhD (Pharm. Sci.) – University of Southern California, Los Angeles, CA
- MPharm (Pharm. Engg.) – Jadavpur University, Kolkata, India
- BPharm (Hons) – BITS, Pilani, India
Affiliations
- University of Colorado Anschutz Medical Campus, Department of Ophthalmology
- Expert Opinion on Drug Delivery (Editor-in-Chief)
- Pharmaceutical Research (Editor)
- Journal of Ocular Pharmacology and Therapeutics (Associate Editor)
- Journal of Ocular Biology, Diseases and Informatics (Member, Editorial Board)
- Clinical Research and Regulatory Affairs (Editor 2004-2008)
- Drug Delivery Technology (Member, Editorial Board)
- International Journal of Pharmaceutical Sciences and Nanotechnology (Member, Editorial Board)
Pharmacokinetics
- HPLC with UV, Fluorescence, PDA
- LC-MS (ThermoScientific MSQ)
- LC-MS-MS (ThermoScientific TSQ Quantum)
- UPLC-MS-MS (ThermoScientific Accela-TSQ Vantage)
Pharmacogenomics
- DNA isolation
- Polymerase Chain Reaction
- Pyrosequencing
Pharmacokinetics
- NONMEM
- PDx-POP
- Pirana
- PsN
- Xpose4
- Phoenix Academic Bundle
- Phoenix WinNonlin
- NLME
- IVIVC
- Connect
- Simcyp Simulator
- Simcyp Animal
- Boomer
Pharmacogenomics
- Biotage Primer Design Software
- PHASE (for haplotype analysis)
Study Design and Statistical Analysis
- PASS Power and Sample Size Software
- SPSS Statistical Analysis Software
- SAS Statistical Analysis Software
Designated as a Center of Excellence for Model-informed Drug Development (MDD)
Our program is designated as a Center of Excellence by Certara, a global leader in biosimulation. We are one of only five pharmacy schools in the nation to receive this designation which allows our students to use Certara’s Phoenix software suite as part of their analyses and method development.