Dr. Bauer is an associate professor in Department of Environmental & Occupational Health at the Colorado School of Public Health. She is a toxicologist that is interested in two central focus areas that are relevant to human health concerns, one for environmental research and one for basic cancer research, both of which generally focus on the mechanisms driving lung tumorigenesis and the associated inflammation. Prior to coming to Colorado, she was a faculty member in the Department of Pathobiology and Center for Integrative Toxicology at Michigan State University and maintained her own environmental and basic cancer laboratory. Her post-doctoral training was at the National Institute for Environmental Health Sciences in the Laboratory of Respiratory Biology with Dr. Steven Kleeberger on environmental genetics. She received her PhD from the University of Colorado Health Sciences Center in Pharmacology in Dr. Al Malkinson’s laboratory and her B.S. in biochemistry from Pennsylvania State University. She has on-going research studies with collaborators at NIEHS, M.D. Anderson, Michigan State University, Ruhr-University, Bochum, Germany, and Masaryk University, Brno, Czech Republic.
Learn more about Dr. Bauer's Research Lab.
Areas of Expertise
- Environmental and occupational lung carcinogenesis, specifically tumor promotion
- Environmental lung toxicants: E-cigarettes and viral infectivity
- Innate immune system in lung inflammation and tumorigenesis
- Innate immune system in ozone-induced lung injury and inflammation
- Novel therapeutic approaches for non-small cell lung cancer and asthma
Education, Licensure & Certifications
- PhD, Pharmacology, University of Colorado Health Sciences Center
- BS, Biochemistry, Pennsylvania State University
Awards
- Paper of the Year, co-author, Inhalation and Respiratory Specialty Section, Society of Toxicology, 2015
- Elected member, Alpha Upsilon Chapter of Delta Omega National Honor Society in Public Health, 2018
- Fellow, American Thoracic Society, 2018
Courses
- EHOH 6616 Environmental and Occupational Toxicology
- EHOH 6643 Air Quality and Public Health
- EHOH 7631 Survey of Environmental & Occupational Health Methods
- EHOH 7632 Advanced Field Methods in Environmental & Occupational Health
Publications and Presentations
- Bauer, A.K., *Xiong, K., Velmurugan, K., *Alexander, C.M., *Xiong, J., and *Brooks, R. 2016 Epiregulin is required for lung tumor promotion in a two-stage carcinogenesis model. Molecular Carcinogenesis, Feb 19. doi: 10.1002/mc.22475.
- Bauer, A.K., Velmurugan, K., Plöttner, S., *Siegrist, K.J., *Romo, D., Welge, P., Brüning, T., Xiong, K., and Käfferlein, H.U. 2017. Environmentally prevalent polycyclic aromatic hydrocarbons elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model. Arch Toxicol. Nov 23. doi: 10.1007/s00204-017-2124-5. [Epub ahead of print]
- Bauer, A.K., Umer, M. Richardson, V.L. Cumpian, A.M., Harder, A.Q. Khosravi, N, Azzegagh, Z. Hara, N.M., Ehre, C., Mohebnasab, M. Caetano, M.S. Merrick, D.T, Van Bokhoven, A. Wistuba, I.I. Kadara, H., Velmurugan, K., Mann, P.R., Lu, X. Barón, A.E. Evans, C.M., Moghaddam, S.J. Requirement for MUC5AC in K-RAS dependent lung carcinogenesis. JCI Insight Aug 9;3(15). pii: 120941. doi: 10.1172/jci.insight.120941. [Epub ahead of print].
- Siegrist, K.S.*, Romo, D. Upham, B.L., Armstrong, M., Quinn, K., Vanderlinden, L.Osgood, R.S., Velmurugan, K., Elie, M.*, Manke, J., Reinhold, D., Reisdorph, N., Saba, L., and Bauer, A.K. Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling. Toxicological Sciences Jan. 20, 2019.
- Romo, D., Velmurugan, K., Upham, B.L., and Bauer, A.K. Dysregulation of gap junction function and cytokine production in response to non-genotoxic polycyclic aromatic hydrocarbons in an in vitro lung cell model. Cancers (Basel). Apr 23;11(4). pii: E572. doi: 10.3390/cancers11040572, 2019.